Magnetic separation and focus of Aβ 1–42 molecules dispersed on the threshold focus for Alzheimer’s illness prognosis in clinically-relevant volumes of pattern | Journal of Nanobiotechnology


  • Scheltens P, De Strooper B, Kivipelto M, Holstege H, Chétalat G, Teunissen CE, Cummings J, van der Flier WM. Alzheimer’s illness. Lancet. 2021;397:1577–90.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Jack CR Jr, Knopman DS, Jagust WJ, Petersen RC, Weiner MW, Aisen PS, Shaw LM, Vemuri P, Wiste HJ, Weigand SD, Lesnick TG, Pankratz VS, Donohue MC, Trojanowski JQ. Monitoring pathophysiological processes in Alzheimer’s illness: an up to date hypothetical mannequin of dynamic biomarkers. Lancet Neurol. 2013;12:207–16.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Musiek ES, Holtzman DM. Three dimensions of the amyloid speculation: time, house and wingmen. Nat Neurosci. 2015;18:800–6.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Fagan AM, Mintun MA, Mach RH, Sang-Yoon L, Dence CS, Shah AR, LaRossa GN, Spinner ML, Klunk WE, Mathis CA, DeKosky ST, Morris JC, Holtzman DM. Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Aβ42 in people. Ann Neurol. 2006;59:512–19.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Le Bastard N, Martin JJ, Vammechelen E, Vanderstichele H, De Deyn PP. Engelborghs S.Added diagnostic worth of CSF biomarkers in differential dementia prognosis. Neurobiol Growing older. 2010;31:1867–76.

    Article 
    PubMed 

    Google Scholar
     

  • Dubois B, Feldman HH, Jacova C, Hampel H, Molinuevo JL, Blennow Ok, Dekosky ST, Gauthier S, Selkoe D, Bateman R, Cappa S, Crutch S, Engelborghs S, Frisoni GB, Fox NC, Galasko D, Habert M-O, Jicha GA, Nordberg A, Pasquier F, Rabinovici G, Robert P, Rowe C, Salloway S, Sarazin M, Epelbaum S, de Souza LC, Vellas B, Visser PJ, Schneider L, Stern Y, Scheltens P, Cummings JL. Advancing analysis diagnostic standards for Alzheimer’s illness: the IWG-2 standards. Lancet Neurol. 2014: 13, 614–29.

  • Cohen AD, Landau SM, Snitz BE, Klunk WE, Blennow Ok, Zetterberg H. Fluid and PET biomarkers for amyloid pathology in Alzheimer’s illness. Mol Cell Neuroscience. 2019;97:3–17.

    Article 
    CAS 

    Google Scholar
     

  • van Dyck CH, Swanson CJ, Aisen P, Bateman RJ, Chen C, Gee M, Kanekiyo M, Li D, Reyderman L, Cohen S, Froelich L, Katayama S, Sabbagh M, Vellas B, Watson D, Dhadda S, Irizarry M, Kramer LD, Iwatsubo T. Lecanemab in early Alzheimer’s illness. New Eng J Med. 2023;388:9–21.

    Article 
    PubMed 

    Google Scholar
     

  • Blennow Ok, Zetterberg H. Biomarkers for Alzheimer’s illness: present standing and prospect for the longer term. J.Int.Med. 2018: 284, 643–63.

  • Blennow Ok, Mattsson N, Schöll M, Hansson O, Zetterberg H. Amyloid biomarkers in Alzheimer’s illness. Tendencies Pharmacol Sci. 2015;36:297–309.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Mattsson N, Andreasson U, Persson S, Carrillo MC, Collins S, Chalbot S, Cutler N, Dufur-Rainfray D, Fagan AM, Heegaard NHH, Hsiung G-YR, Hyman B, Iqbal Ok, Lachno DR, Lleó A, Lewczuk P, Molinuevo JL, Parchi P, Regeniter A, Rissman R, Rosenmann H, Sancesario G, Schröder J, Shaw LM, Teunissen CE, Trojanowski JQ, Vanderstichele H, Vandijck M, Verbeek MM, Zetterberg H, Blennow Ok. Käser SA and the Alzheimer’s Affiliation QC Program Work Group. CSF Biomarker variability within the Alzheimer’s Affiliation high quality management program. Alzheimer’s&Dementia 2013: 9, 251–61.

  • Perret-Liaudet A, Pelpel M, Tholance Y, Dumont B, Vanderstichele H, Zorzi W, ElMoualij B, Schraen S, Moreaud O, Gabelle A, Thouvenot E, Thomas-Anterion C, Touchon J, Krolak-Salmon P, Kovacs GG, Coudreuse A, Quadrio I, Lehmann S. Threat of Alzheimer’s illness organic misdiagnosis linked to cerebrospinal assortment tubes. J Alzheimers Dis. 2012;31:13–20.

    Article 
    PubMed 

    Google Scholar
     

  • Van Thanh Nguyen N, Taverna M, Smadja C, Mai TD. Latest electrokinetic and microfluidic methods for detection of amyloid beta peptide biomarkers: in the direction of molecular prognosis of Alzheimer’s illness. Chem.Rec. 2021: 21, 149–61.

  • Wu Ok, Su D, Liu J, Saha R, Wang J-P. Magnetic nanoparticles in nanomedicine: a evaluate of current advances. Nanotechnology. 2019;30:502003.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Squires TM, Quake SR. Microfluidics: fluid physics on the nanoliter scale. Rev Mod Physics. 2005;77:977–1026.

    Article 
    CAS 

    Google Scholar
     

  • Kiplagat A, Martin DR, Onani MO, Meyer M. Aptamer-conjugated magnetic nanoparticles for the environment friendly seize of most cancers biomarker proteins. J.Magn.Magn.Mat. 2020: 497, 166063.

  • Tang C, He Z, Liu H, Xu Y, Huang H, Yang G, Xiao Z, Li S, Liu H, Deng Y, Chen Z, Chen H, He N. Software of magnetic nanoparticles in nucleic acid detection. J Nanobiotechnol. 2020;18:62.

    Article 

    Google Scholar
     

  • Zhao Z, Cui H, Tune W, Ru X, Zhou W, Yu X. A easy magnetic nanoparticles-based viral RNA extraction technique for environment friendly detection of SARS-Co-V-2. bioRxiv 2020.02.22.961268 (2020).

  • Cudjoe KS, Krona R. Detection of Salmonella from uncooked meals samples utilizing Dynabeads® anti-Salmonella and a traditional reference technique. Int J Meals Microbiol. 1997;37:55–62.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Vardal F, Gaudernack G, Funderud S, Bratile A, Lea T, Ugelstad J, Thorsby E. HLA class I and II typing utilizing cells positively chosen from blood by immunomagnetic isolation–a quick and dependable approach. Tissues Antigens. 1986: 28, 301–12.

  • Saei A, Asfia S, Kouchakzadeh H, Rahmandoust M. Antibody-modified magnetic nanoparticles as particular high-efficient cell-separation brokers. J Biomed Mater Res. 2020;108B:2633–42.

    Article 
    CAS 

    Google Scholar
     

  • Yang J, Pan B, Zeng F, He B, Gao Y, Liu X, Tune Y. Magnetic colloid antibodies speed up small extracellular vesicles isolation for point-of-care diagnostics. NanoLett. 2021: 21, 2001–9.

  • Ramadan Q, Gijs MAM. Simultaneous pattern washing and focus utilizing a trapping-and-releasing mechanism of magnetic beads on a microfluidic chip. Analyst. 2011;136:1157–66.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Johansson LE, Gunnarsson Ok, Bijelovic S, Eriksson Ok, Surpi A, Göthelid E, Svedlindh P, Oscarsson S. A magnetic microchip for managed transport of attomole ranges of proteins. Lab.Chip. 2010: 10, 654–61.

  • Lee CS, Lee H, Westervelt RM. Microelectromagnets for the management of magnetic nanoparticles. Appl Phys Lett. 2001;79:3308–10.

    Article 
    CAS 

    Google Scholar
     

  • Donolato M, Vavassori P, Gobbi M, Deryabina M, Hansen MF, Metlushko V, Ilic B, Cantoni M, Petti D, Brivio S, Bertacco R. On-chip manipulation of protein-coated magnetic beads through domain-wall conduits. Adv Mat. 2010;22:2706–10.

    Article 
    CAS 

    Google Scholar
     

  • Wang J, Morabito Ok, Erkers T, Tripathi A. Seize and separation of biomolecules utilizing magnetic beads in a easy microfluidic channel with out an exterior move system. Analyst. 2013;138:6573–81.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Tarn MD, Peyman SA, Pamme N. Simultaneous trapping of magnetic and diamagnetic particle plugs for separations and bioassays. RCS Adv. 2013;3:7209–14.

    CAS 

    Google Scholar
     

  • Blümler P. Magnetic guiding with everlasting magnets: idea, realization and purposes to nanoparticles and cells. Cells. 2021;10:2708.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Surpi A, Shelyakova T, Murgia M, Rivas J, Piñeiro Y, Greco P, Fini M, Dediu VA. Versatile magnetic configuration and manipulations for the management and manipulation of superparamagnetic nanoparticles. Sci Rep. 2023;13:5301.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Willemse EAJ, Tijms BM, van Berckel BNM, Le Bastard N, van der Flier WM, Scheltens P, Teunissen CE. Evaluating CSF amyloid-beta biomarker ratios for 2 automated immunoassays, Elecsys and Lumipulse, with amyloid PET standing. Alzheimer’s Dement. 2021: 13, e12182.

  • Gonzales Gomez MA, Belderbos S, Yañez-Villar S, Piñero Y, Cleeren F, Bormans G, Deroose CM, Gsell W, Himmelreich U, Rivas J. Growth of superparamagnetic nanoparticles coated with polyacrylic acid and aluminum hydroxide as an environment friendly distinction agent for multimodal imaging. Nanomaterials. 2019;9:1626.

    Article 

    Google Scholar
     

  • Moldes-Diz Y, Gamallo M, Eibes G, Vargas-Osorio Z, Vazquez-Vazquez C, Feijoo G, Lema JM, Moreira MT. Growth of a superparamagnetic laccase nanobiocatalyst for the enzymatic biotransformation of xenobiotics. J Environ Eng. 2018;144:04018007.

    Article 

    Google Scholar
     

  • Karaagac O, Kockar H. A easy strategy to receive excessive saturation magnetization for superparamagnetic iron oxide nanoparticles synthesized in air environment: optimization by experimental design. J.Magn.Magn.Mat. 2016: 409, 116–23.

  • García Acevedo P, González Gómez MA, Arnosa Prieto A, De Castro Alves L, Seco Gudiña R, Piñeiro Y, Rivas J. Fluorescent single-core and multi-core nanoprobes as cell trackers and magnetic nano heaters. Magnetochemistry. 2022;8:83.

    Article 

    Google Scholar
     

  • Baig MH, Ahmad Ok, Rabbani G, Choi I. Use of peptides for the administration of Alzheimer’s illness: prognosis and inhibition. Entrance.Growing older.Neurosci. 2018: 10, 21.

  • Watanabe Ok-I, Nakamura Ok, Akikusa S, Okada T, Kodaka M, Konakahara T, Okuno H. Inhibitors of fibril formation and cytoxicity of β-amyloid peptide composed of KLVFF recognition component and versatile hydrophilic disrupting component. Biochem Biophys Res Commun. 2002;290:121–4.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Rozga M, Bittner T, Höglund Ok, Blennow Ok. Accuracy of cerebrospinal fluid Aβ1–42 measurements: analysis of pre-analytical elements utilizing a novel Elecsys immunoassay. Clin Chem Lab Med. 2017;55:1545–54.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Gobom J, Parnetti L, Rosa-Neto P, Vyhnalek M, Gauthier S, Cataldi S, Lerch O, Laczo J, Cechova Ok, Clarin M, Benet AL, Pascoal TA, Rahmouni N, Vandijck M, Huyck E, Le Bastard N, Stevenson J, Chamoun M, Alcolea D, Lleó A, Andreasson U, Verbeek MM, Bellomo G, Rinaldi R, Ashton NJ, Zetterberg H, Sheardova Ok, Hort J, Blennow Ok. Validation of the LUMIPULSE automated immunoassay for the measurement of core AD biomarkers in cerebrospinal fluid. Clin Chem Lab Med. 2022;60:207–19.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Leitão MJ, Silva-Spínola A, Santana I, Olmedo V, Nadal A, Le Bastard N, Baldeiras I. Medical validation of the Lumipulse G cerebrospinal fluid assays for routine prognosis of Alzheimer’s illness. Alzheimer’s Res Ther. 2019;11:91.

    Article 

    Google Scholar
     

  • D’Oronzo S, Brown J, Coleman R. The function of biomarkers within the administration of bone-homing malignancies. J Bone Oncol. 2017;9:1–9.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Singh VK, Newman VL, Romaine PLP, Hauer-Jensen M, Pollard HB. Use of biomarkers for assessing radiation damage and efficacy of countermeasures. Skilled Rev Mol Diagn. 2016;16:65–81.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Wang J, Lu P, Yan J, Zhang Y, Huang L, Ali Z, Liu B, Li Z, He N. Speedy and delicate detection of RNA viruses based mostly on reverse transcription loop-mediated isothermal amplification, magnetic nanoparticles, and chemiluminescence. J Biomed Nanotechnol. 2016;12:710–6.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Cui H, Tune W, Ru X, Fu W, Ji L, Zhou W, Zhao Z, Qu G, Yu X-F, Jiang G. A simplified viral RNA extraction technique based mostly on magnetic nanoparticles for quick and high-throughput detection of SARS-CoV-2. Talanta. 2023;258:124479.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

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