Summary
Bilirubin is a key biomarker within the prognosis of jaundice. Herein, we proposed a easy and handy quantitative methodology for the fluorescent detection of bilirubin. We developed a copper nanoclusters coated by zinc-based metal-organic frameworks (Cu NCs@MOF). The ready Cu NCs@MOF exhibited brilliant blue fluorescence excited with ultra-violet gentle and effectively stability at numerous environments. Extra importantly, Cu NCs@MOF was used for bilirubin detection based mostly on the rising crimson fluorescence emission peak induced by bilirubin. Moreover, Cu NCs@MOF had been made into take a look at strip for the visible detection of bilirubin by the fluorescence coloration variation.
Disclosure assertion
The authors declare no competing monetary curiosity.
Scheme 1. The illustration of the preparation technique of ZIF8@Cu NCs and the detection for BR.
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